File:Gene-Dosage-Effects-at-the-Imprinted-Gnas-Cluster-pone.0065639.s002.ogv
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Gene-Dosage-Effects-at-the-Imprinted-Gnas-Cluster-pone.0065639.s002.ogv (Ogg Theora video file, length 27 s, 787 × 576 pixels, 1.26 Mbps, file size: 3.99 MB)
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[edit]DescriptionGene-Dosage-Effects-at-the-Imprinted-Gnas-Cluster-pone.0065639.s002.ogv |
English: Hyperactivity in PatDp(dist2). Video of a 6 day old PatDp(dist2) and wild-type littermate showing almost continual activity and rapid movement with paddling of the front feet in the PatDp(dist2) but very little movement in the wild-type. The PatDp(dist2) has the characteristic tail kink or bend, and by 6 days is clearly smaller than the wild-type but oedema and a chunky appearance are no longer evident. The mice have a genetic background that is 50% Mus musculus castaneus and 50% laboratory mouse. On this background there was slightly better survival of PatDp(dist2) to 7 days (10/23) compared with 3/28 on an entirely laboratory mouse background (P = 0.0106 (Fisher’s exact test, 2-tailed) but no difference in survival to weaning. |
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Source | Video S1 from Ball S, Kelly M, Robson J, Turner M, Harrison J, Jones L, Napper D, Beechey C, Hough T, Plagge A, Cattanach B, Cox R, Peters J (2013). "Gene Dosage Effects at the Imprinted Gnas Cluster". PLOS ONE. DOI:10.1371/journal.pone.0065639. PMC: 3688811. | ||
Author | Ball S, Kelly M, Robson J, Turner M, Harrison J, Jones L, Napper D, Beechey C, Hough T, Plagge A, Cattanach B, Cox R, Peters J | ||
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 17:48, 4 July 2013 | 27 s, 787 × 576 (3.99 MB) | Open Access Media Importer Bot (talk | contribs) | Automatically uploaded media file from Open Access source. Please report problems or suggestions here. |
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Author | Ball S, Kelly M, Robson J, Turner M, Harrison J, Jones L, Napper D, Beechey C, Hough T, Plagge A, Cattanach B, Cox R, Peters J |
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Usage terms | http://creativecommons.org/licenses/by/3.0/ |
Image title | Hyperactivity in PatDp(dist2). Video of a 6 day old PatDp(dist2) and wild-type littermate showing almost continual activity and rapid movement with paddling of the front feet in the PatDp(dist2) but very little movement in the wild-type. The PatDp(dist2) has the characteristic tail kink or bend, and by 6 days is clearly smaller than the wild-type but oedema and a chunky appearance are no longer evident. The mice have a genetic background that is 50% Mus musculus castaneus and 50% laboratory mouse. On this background there was slightly better survival of PatDp(dist2) to 7 days (10/23) compared with 3/28 on an entirely laboratory mouse background (P? |
Software used | Xiph.Org libtheora 1.1 20090822 (Thusnelda) |
Date and time of digitizing | 2013 |