File:High-Grade SIL.jpg

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Summary[edit]

Description

High-grade squamous intraepithelial lesion, abbreviated HSIL, also known as high-grade dysplasia.

24-year-old woman with normal conventional Pap in 2003. This one is a ThinPrep.

If you're lucky, a case of high-grade dysplasia will be like this one, a conspicuous group of distinct dark cells with variation of nuclear size and shape, heavy chromatin, and high nuclear/cytoplasmic ratio. These can really stand out.

If you're unlucky, the cells of HSIL can be infrequent, individual, and bland-appearing. Paradoxically, it's easier to overlook a high-grade lesion in ThinPrep than a low-grade one, and the most serious lesions of all--invasive carcinomas--are the easiest of all to miss.

See also

Date
Source https://www.flickr.com/photos/euthman/384709978/in/set-72057594114099781/
Author Ed Uthman, MD
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Checked copyright icon.svg This image was originally posted to Flickr by euthman at https://www.flickr.com/photos/78147607@N00/384709978. It was reviewed on by FlickreviewR and was confirmed to be licensed under the terms of the cc-by-sa-2.0.

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current22:40, 1 April 2007Thumbnail for version as of 22:40, 1 April 2007776 × 675 (409 KB)Patho (talk | contribs)== Summary == {{Information |Description='''High-Grade SIL''' 24-year-old woman with normal conventional Pap in 2003. This one is a ThinPrep. If you're lucky, a case of high-grade dysplasia will be like this one, a conspicuous group of distinct dark cel
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