File:Hypothalamo–pituitary–adrenal (HPA) stress axis.jpg

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English: The hypothalamo–pituitary–adrenal (HPA) stress axis. The neuropeptides corticotropin-releasing hormone (CRH) and arginine vasopressin (AVP) are expressed in the parvocelluar neurons of the hypothalamic nucleus paraventricularis. The joint release of CRH and AVP into the portal blood vessels leads to potent stimulation of anterior pituitary ACTH secretion and in turn of corticosterone from the adrenal glands. The activational effects of the HPA axis are counteracted by the inhibitory effects of glucocorticoid receptors expressed in the hippocampus, hypothalamus, and anterior pituitary.
Date Published online: 18 April 2011.
Source Murgatroyd C and Spengler D (2011) Epigenetics of early child development. Front. Psychiatry 2:16. doi: 10.3389/fpsyt.2011.00016 http://journal.frontiersin.org/article/10.3389/fpsyt.2011.00016/full
Author Murgatroyd C and Spengler D

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current16:30, 31 October 2015Thumbnail for version as of 16:30, 31 October 2015654 × 619 (252 KB)Was a bee (talk | contribs){{Information |Description={{en|1=The hypothalamo–pituitary–adrenal (HPA) stress axis. The neuropeptides corticotropin-releasing hormone (CRH) and arginine vasopressin (AVP) are expressed in the parvocelluar neurons of the hypothalamic nucleus para...

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