File:Key-Bifurcations-of-Bursting-Polyrhythms-in-3-Cell-Central-Pattern-Generators-pone.0092918.s003.ogv
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[edit]DescriptionKey-Bifurcations-of-Bursting-Polyrhythms-in-3-Cell-Central-Pattern-Generators-pone.0092918.s003.ogv |
English: Multistable dynamics of an asymmetric 3-cell CPG: from pattern to sudden death. Bursting trajectory (gray) in the 3D phase space of the model, which is made of the “active” spiking (solenoid-like shaped) and the flat hyperpolarized sections. The gap between the 2D slow nullcline, , and the low knee on the slow quiescent manifold, , determines the amount of inhibition needed by the active pre-synaptic cell above the synaptic threshold, , to either slow or hold the post-synaptic cell(s) at a hyperpolarized level around . The red, green and blue spheres on the bursting trajectory depict the temporal evolution of the the phases of the [not weekly]-coupled cells of the CPG: active cell(s) above inhibits, in anti-phase, the temporarily inactive cells and visa versa. Inhibitory pulse applied to the blue cell changes the relative phases of the bursting cells so that the pacemaking red cell, leading initially the rhythm, becomes permanently inhibited by the blue and green cells bursting in alternation. Below are shown the corresponding voltage waveforms. This motion picture complements Fig. 29. |
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Source | Movie S3 from Wojcik J, Schwabedal J, Clewley R, Shilnikov A (2014). "Key Bifurcations of Bursting Polyrhythms in 3-Cell Central Pattern Generators". PLOS ONE. DOI:10.1371/journal.pone.0092918. PMID 24739943. PMC: 3989192. | ||
Author | Wojcik J, Schwabedal J, Clewley R, Shilnikov A | ||
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This file is licensed under the Creative Commons Attribution 4.0 International license.
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Author | Wojcik J, Schwabedal J, Clewley R, Shilnikov A |
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Usage terms | http://creativecommons.org/licenses/by/4.0/ |
Image title | Multistable dynamics of an asymmetric 3-cell CPG: from pattern to sudden death. Bursting trajectory (gray) in the 3D phase space of the model, which is made of the ?active? spiking (solenoid-like shaped) and the flat hyperpolarized sections. The gap between the 2D slow nullcline, , and the low knee on the slow quiescent manifold, , determines the amount of inhibition needed by the active pre-synaptic cell above the synaptic threshold, , to either slow or hold the post-synaptic cell(s) at a hyperpolarized level around . The red, green and blue spheres on the bursting trajectory depict the temporal evolution of the the phases of the [not weekly]-coupled cells of the CPG: active cell(s) above inhibits, in anti-phase, the temporarily inactive cells and visa versa. Inhibitory pulse applied to the blue cell changes the relative phases of the bursting cells so that the pacemaking red cell, leading initially the rhythm, becomes permanently inhibited by the blue and green cells bursting in alternation. Below are shown the corresponding voltage waveforms. This motion picture complements Fig. 29. |
Software used | Xiph.Org libtheora 1.1 20090822 (Thusnelda) |
Date and time of digitizing | 2014 |