File:Ligand-specific-endocytic-dwell-times-control-functional-selectivity-of-thecannabinoid-receptor-1-ncomms5589-s3.ogv

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Ligand-specific-endocytic-dwell-times-control-functional-selectivity-of-thecannabinoid-receptor-1-ncomms5589-s3.ogv(Ogg Theora video file, length 55 s, 371 × 371 pixels, 585 kbps, file size: 3.81 MB)

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English: Supplementary Movie 2 Imaging CB1Rs endocytosis by TIRF microscopy. Simultaneous dual fluorescence

TIRF microscopy series (0.3Hz) from a HEK cell co-expressing SEP-CB1R and RFP-β-arrestin-2. Endocytosis was initiated with 5 μM WIN 55,212-2, resulting in receptor clustering, beta-arrestin recruitment and

endocytosis. Total running time= 30 minutes.
Date
Source Video file from Flores-Otero J, Ahn K, Delgado-Peraza F, Mackie K, Kendall D, Yudowski G (2014). "Ligand-specific endocytic dwell times control functional selectivity of the cannabinoid receptor 1". Nature Communications. DOI:10.1038/ncomms5589. PMID 25081814. PMC: 4227836.
Author Flores-Otero J, Ahn K, Delgado-Peraza F, Mackie K, Kendall D, Yudowski G
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Date/TimeThumbnailDimensionsUserComment
current13:10, 2 November 201655 s, 371 × 371 (3.81 MB)Open Access Media Importer Bot (talk | contribs)Automatically uploaded media file from Open Access source. Please report problems or suggestions here.

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