File:Mechanosensitive-Enteric-Neurons-in-the-Myenteric-Plexus-of-the-Mouse-Intestine-pone.0039887.s001.ogv

English: Activation of enteric mechanosensitive neurons by ganglionic deformation. Slow motion movie of the ganglionic deformation during intraganglionic volume injection (original length 1.3 s). The outlines of the neurons are visible because the voltage sensitive dye Di-8-ANEPPS incorporates into the outer membrane. The movie shows the deformation during the volume injection and at the same time the colour coded action potential discharge (red flashes). Locations of the 2 neurons that fire action potentials in response to intraganglionic volume injection are indicated by red arrows. Note that with this magnification activity in one neuron is detected by several pixels. The two traces to the left show the responses of the two mechanosensitive neurons. Each action potential corresponds to the colour coded activity (red flashes). In the upper part of the movie onsets of the dynamic and sustained deformations are indicated.