File:Murid-Herpesvirus-4-Exploits-Dendritic-Cells-to-Infect-B-Cells-ppat.1002346.s003.ogv

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Original file ‎(Ogg Theora video file, length 7.1 s, 2,048 × 1,024 pixels, 7.87 Mbps, file size: 6.7 MB)

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English: Bone marrow-derived DCs were infected with gM-eGFP+ MuHV-4 (3 p.f.u./cell) and imaged 6 h later by time-lapse confocal microscopy (Leica). Images were recorded every 8 sec over 7 min. The left-hand panel shows eGFP fluoresence and the right-hand panel the corresponding phase contrast image. At 6 h after exposure to MuHV-4, DCs show little late lytic gene expression. Thus the eGFP signal comes from the input virions. The non-adherent DCs correspond to those more activated prior to virus exposure, which are poorly infected and so remain eGFP-. The DCs taking up virions, and presumably becoming infected, show flattening, adherence to plastic and marked cytoplasmic motility.
Date
Source Video S1 from Gaspar M, May J, Sukla S, Frederico B, Gill M, Smith C, Belz G, Stevenson P (2011). "Murid Herpesvirus-4 Exploits Dendritic Cells to Infect B Cells". PLOS Pathogens. DOI:10.1371/journal.ppat.1002346. PMID 22102809. PMC: 3213091.
Author Gaspar M, May J, Sukla S, Frederico B, Gill M, Smith C, Belz G, Stevenson P
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This file was published in a Public Library of Science journal. Their website states that the content of all PLOS journals is published under the Creative Commons Attribution 4.0 license (or its previous version depending on the publication date), unless indicated otherwise.
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current01:24, 18 November 20127.1 s, 2,048 × 1,024 (6.7 MB)Open Access Media Importer Bot (talk | contribs)Automatically uploaded media file from Open Access source. Please report problems or suggestions here.

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VP9 1080P 3.81 Mbps Completed 02:24, 4 September 2018 17 s
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Streaming 144p (MJPEG) 275 kbps Completed 06:52, 15 November 2023 1.0 s

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