File:Neutralizing antibodies for treating COVID-19.tif
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DescriptionNeutralizing antibodies for treating COVID-19.tif |
English: Development of neutralizing antibodies for treating COVID-19. In the receptor binding stage, the S1 subunit of SARS-CoV-2 binds human ACE2 on the host cell surface. Antibodies that bind the RBD domain on the S1 subunit might block the interaction of the RBD and the ACE2. In the viral fusion stage, after the cleavage of S1 subunit, the viral fusion peptide (FP) on the S2 subunit inserts into the host cell membrane, inducing the conformational change of the S2 subunit, which forms a six-helix bundle (6-HB) with the HR1 and HR2 trimers. Antibodies that target the HR domains might block viral fusion. Ab, antibody. |
Date | |
Source | Own work |
Author | Bioshore |
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 16:29, 14 June 2020 | 2,100 × 750 (573 KB) | Bioshore (talk | contribs) | Cross-wiki upload from en.wikipedia.org |
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Width | 2,100 px |
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Height | 750 px |
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Compression scheme | LZW |
Pixel composition | RGB |
Orientation | Normal |
Number of components | 3 |
Number of rows per strip | 41 |
Horizontal resolution | 300 dpi |
Vertical resolution | 300 dpi |
Data arrangement | chunky format |
Software used | Adobe Photoshop 21.1 (Windows) |
File change date and time | 08:41, 7 May 2020 |
Color space | Uncalibrated |