File:Permanent-Occlusion-of-Feeding-Arteries-and-Draining-Veins-in-Solid-Mouse-Tumors-by-Vascular-pone.0010282.s005.ogv
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Permanent-Occlusion-of-Feeding-Arteries-and-Draining-Veins-in-Solid-Mouse-Tumors-by-Vascular-pone.0010282.s005.ogv (Ogg Theora video file, length 47 s, 696 × 512 pixels, 83 kbps, file size: 475 KB)
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[edit]DescriptionPermanent-Occlusion-of-Feeding-Arteries-and-Draining-Veins-in-Solid-Mouse-Tumors-by-Vascular-pone.0010282.s005.ogv |
English: Tookad-VTP induced blood clotting. Circulating platelets and leukocytes were stained in vivo with Rhodamine 6 G immediately before sensitizer injection. FA and DV at “vascular junction 1” were monitored before and during Tookad-VTP. Formation of blood clots on the inner FA walls, particularly at pre-capillary bifurcation points was observed soon after VTP onset (tVTP = 17 sec), and correlated with vessel constriction (tVTP∼34 sec, peaking at tVTP∼60 sec). This was followed by mobilization of blood clots towards the interface of the tumor microcirculation with subsequent vessel occlusion. |
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Source | Video S5 from Madar-Balakirski N, Tempel-Brami C, Kalchenko V, Brenner O, Varon D, Scherz A, Salomon Y (2010). "Permanent Occlusion of Feeding Arteries and Draining Veins in Solid Mouse Tumors by Vascular Targeted Photodynamic Therapy (VTP) with Tookad". PLOS ONE. DOI:10.1371/journal.pone.0010282. PMID 20421983. PMC: 2858664. | ||
Author | Madar-Balakirski N, Tempel-Brami C, Kalchenko V, Brenner O, Varon D, Scherz A, Salomon Y | ||
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 03:38, 17 November 2012 | 47 s, 696 × 512 (475 KB) | Open Access Media Importer Bot (talk | contribs) | Automatically uploaded media file from Open Access source. Please report problems or suggestions here. |
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Author | Madar-Balakirski N, Tempel-Brami C, Kalchenko V, Brenner O, Varon D, Scherz A, Salomon Y |
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Usage terms | http://creativecommons.org/licenses/by/3.0/ |
Image title | Tookad-VTP induced blood clotting. Circulating platelets and leukocytes were stained in vivo with Rhodamine 6 G immediately before sensitizer injection. FA and DV at ?vascular junction 1? were monitored before and during Tookad-VTP. Formation of blood clots on the inner FA walls, particularly at pre-capillary bifurcation points was observed soon after VTP onset (tVTP? |
Software used | Xiph.Org libtheora 1.1 20090822 (Thusnelda) |
Date and time of digitizing | 2010 |