File:RIPK3-promotes-cell-death-and-NLRP3-inflammasome-activation-in-the-absence-of-MLKL-ncomms7282-s2.ogv

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English: Supplementary Movie 1 LPS and Cp. A induced cell death. CTG labeled WT, Ripk3-/- and Ripk3-/-Caspase-8-/- BMDM were primed for 2 hrs with LPS (20 ng/ml), and in the final 20 min Q-VD-OPh (20 μM) was added as indicated. Macrophages were then stimulated with Cp.A (500 nM) where indicated and PI added prior to time lapse imaging. Images were taken from 4 hrs post priming at 30 min intervals (green = CTG, red = PI; 4 frames/sec, 10X magnification) and movies made using Image J software.
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Source Video file from Lawlor K, Khan N, Mildenhall A, Gerlic M, Croker B, D’Cruz A, Hall C, Kaur Spall S, Anderton H, Masters S, Rashidi M, Wicks I, Alexander W, Mitsuuchi Y, Benetatos C, Condon S, Wong W, Silke J, Vaux D, Vince J (2015). "RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL". Nature Communications. DOI:10.1038/ncomms7282. PMID 25693118. PMC: 4346630.
Author Lawlor K, Khan N, Mildenhall A, Gerlic M, Croker B, D’Cruz A, Hall C, Kaur Spall S, Anderton H, Masters S, Rashidi M, Wicks I, Alexander W, Mitsuuchi Y, Benetatos C, Condon S, Wong W, Silke J, Vaux D, Vince J
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Date/TimeThumbnailDimensionsUserComment
current20:26, 1 November 20167.0 s, 2,076 × 1,560 (7.7 MB)Open Access Media Importer Bot (talk | contribs)Automatically uploaded media file from Open Access source. Please report problems or suggestions here.

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VP9 1440P 5.58 Mbps Completed 18:48, 16 October 2018 17 s
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