File:Targeting-CD28-CTLA-4-and-PD-L1-Costimulation-Differentially-Controls-Immune-Synapses-and-Function-pone.0083139.s005.ogv
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Targeting-CD28-CTLA-4-and-PD-L1-Costimulation-Differentially-Controls-Immune-Synapses-and-Function-pone.0083139.s005.ogv (Ogg Theora video file, length 15 s, 129 × 96 pixels, 57 kbps, file size: 105 KB)
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[edit]DescriptionTargeting-CD28-CTLA-4-and-PD-L1-Costimulation-Differentially-Controls-Immune-Synapses-and-Function-pone.0083139.s005.ogv |
English: CD28 antagonists induce long lasting contacts between human Treg and APCs. Representative time-lapse video similar to Movie S4 (over 25 minutes), performed in the presence of 10 µg/ml FR104, an antagonist anti-CD28 antibody. Treg (green) become red showing an increase of intracellular calcium flux and thus Treg activation. Contact-time, motility are shown in Fig. 3C, D, H, I and J. Calcium responses are shown in Fig. 4C and D. |
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Source | Movie S5 from Dilek N, Poirier N, Hulin P, Coulon F, Mary C, Ville S, Vie H, Clemenceau B, Blancho G, Vanhove B (2013). "Targeting CD28, CTLA-4 and PD-L1 Costimulation Differentially Controls Immune Synapses and Function of Human Regulatory and Conventional T-Cells". PLOS ONE. DOI:10.1371/journal.pone.0083139. PMC: 3871694. | ||
Author | Dilek N, Poirier N, Hulin P, Coulon F, Mary C, Ville S, Vie H, Clemenceau B, Blancho G, Vanhove B | ||
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This file is licensed under the Creative Commons Attribution 4.0 International license.
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 01:57, 31 December 2013 | 15 s, 129 × 96 (105 KB) | Open Access Media Importer Bot (talk | contribs) | Automatically uploaded media file from Open Access source. Please report problems or suggestions here. |
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This file contains additional information such as Exif metadata which may have been added by the digital camera, scanner, or software program used to create or digitize it. If the file has been modified from its original state, some details such as the timestamp may not fully reflect those of the original file. The timestamp is only as accurate as the clock in the camera, and it may be completely wrong.
Author | Dilek N, Poirier N, Hulin P, Coulon F, Mary C, Ville S, Vie H, Clemenceau B, Blancho G, Vanhove B |
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Usage terms | http://creativecommons.org/licenses/by/4.0/ |
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Software used | Xiph.Org libtheora 1.1 20090822 (Thusnelda) |
Date and time of digitizing | 2013 |