File:Ten generations of backcrossing .gif
Jump to navigation
Jump to search
No higher resolution available.
Ten_generations_of_backcrossing_.gif (472 × 396 pixels, file size: 29 KB, MIME type: image/gif)
Captions
Captions
Add a one-line explanation of what this file represents
| Description |
English: Replacing a detrimental allele. (A) A purebred dog from a breed carrying the dominant functional allele is crossed to a purebred dog from a breed homozygous for an inactivating mutation (P1 cross). Progeny of this cross carrying the normal allele are selected and crossed to purebred animals from the breed of interest. In each generation, those carrying the normal allele are chosen for breeding to purebred animals. Eventually it would be possible to mate two animals that are both heterozygous for the desired allele and produce homozygous progeny, with very little change in genetic composition (B) After five generations of backcrossing to the desired breed, the proportion of the genotype contributed by this breed is 96.9%, while by ten generations it is 99.9%. |
| Date | Published online 2015 Feb 11 |
| Source | Farrell LL, Schoenebeck JJ, Wiener P, Clements DN, Summers KM. The challenges of pedigree dog health: approaches to combating inherited disease. Canine Genetics and Epidemiology. 2015;2:3. doi:10.1186/s40575-015-0014-9. http://cgejournal.biomedcentral.com/articles/10.1186/s40575-015-0014-9 |
| Author | Lindsay L Farrell, Jeffrey J Schoenebeck, Pamela Wiener, Dylan N Clements and Kim M Summers |
| Permission (Reusing this file) |
This is an Open Access article distributed under the terms of the Creative Commons Attribution License |
  This file is licensed under the Creative Commons Attribution 2.0 Generic license.
|
This file was published in a BioMed Central journal. Their website states that all of its research publications is published under the license which is identical to the Creative Commons Attribution 2.0 license (some non-research articles like reviews or editorials may require a subscription.)
To the uploader: You must provide a link (URL) to the original file or journal article.
|
File history
Click on a date/time to view the file as it appeared at that time.
| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 09:25, 25 February 2017 | | 472 × 396 (29 KB) | Was a bee (talk | contribs) | {{Information |Description={{en|1=Replacing a detrimental allele. (A) A purebred dog from a breed carrying the dominant functional allele is crossed to a purebred dog from a breed homozygous for an inactivating mutation (P1 cross). Progeny of this cros... |
You cannot overwrite this file.
File usage on Commons
The following page uses this file:
- File:40575 2015 14 Fig3 HTML.gif (file redirect)
