File:Three-way differential expression (DE) plot shows three distinct states in the T. gondii wild-type asexual cycle.tif
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[edit]DescriptionThree-way differential expression (DE) plot shows three distinct states in the T. gondii wild-type asexual cycle.tif |
English: This plot slices the 8058 predicted T. gondii genes, (each point represents a gene) into specific gene sets that reflect all possible comparisons of intracellular tachyzoites (IT), extracellular tachyzoites (ET) and bradyzoites after 72 hr induction (B72); (IT – ET, B72 – ET, and B72 – IT). Each comparison is associated with a dashed axis, which captures the magnitude of differential expression associated with the comparison, and two solid lines, which bound the set of genes differentially expressed less than 2-fold by the comparison. Of the 8,058 probe sets, 6,096 (central hexagon) are not changed more than 2-fold between any of the 3 states. The extracellular tachyzoite-specific genes lie at the intersection between genes that are up-regulated in extracellular tachyzoites compared to intracellular tachyzoites (IT-ET ≤−1; n = 419, below the green solid line) and genes that are upregulated in extracellular tachyzoites compared to bradyzoites (B72-ET ≤−1; n = 447, to the left of the red solid line), which total 122 genes. The intracellular tachyzoite-specific genes lie at the intersection between genes that are up-regulated in intracellular tachyzoites compared to extracellular tachyzoites (IT-ET ≥1; n = 609, above the green solid line) and genes that are up-regulated in intracellular tachyzoites compared to bradyzoites (B72-IT ≤−1; n = 308, above the blue solid line), which total 149 genes. And, the bradyzoite-specific genes lie at the intersection between genes that are up-regulated in bradyzoites compared to extracellular tachyzoites (B72-ET≥1; n = 738, to the right of the red solid line) and genes that are up-regulated in bradyzoites compared to intracellular tachyzoites (B72-IT≥1; n = 604, below the blue solid line), which total 418 genes. |
Date | |
Source | Template:P Lescault B Thompson, V Patil, D Lirussi, A Burton, J Margarit, J Bond M Matrajt (PLoS One. 2010. 5(12)) |
Author | Plescault |
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 02:04, 6 November 2017 | 1,470 × 1,132 (620 KB) | Plescault (talk | contribs) | User created page with UploadWizard |
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Software used | Adobe Photoshop CS2 Windows |
File change date and time | 16:50, 29 December 2010 |
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