File:A. M. A. archives of neurology and psychiatry (1919) (14757567486).jpg

Identifier: amaarchivesofneu08ameruoft (find matches)
Title: A. M. A. archives of neurology & psychiatry
Year: 1919 (1910s)
Authors: American Medical Association
Subjects: Neurology Psychiatry
Publisher: (Chicago) American Medical Association
Contributing Library: Gerstein - University of Toronto
Digitizing Sponsor: University of Toronto

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peat) they havenever been demonstrated antemortem with the microscope, although afew of the many experiments with animals have apparently shown thatspirochetes may at times exist in the blood of patients with generalparalysis. Spirochetes are strongly resistant to decomposition, and the deadorganisms have been demonstrated in the brain about thirtv days afterdecomposition had been allowed to go on. 594 .■\l<CI(l\liS OF XEUROLOGV AXD PSYCIIIATKY FORM CF SIMKi)(in-:Ti:S IX GFNKRAL I•AKAL^■S1S ANDIN S^•1•11ILIS No difference in f(jrni, shape or size has been established betweenthe spirochetes of general paralysis and those found in ordinary syjjhilis.Noguchi described, in general paralysis, at least three morphologicv^arieties—small, medium and large—and the same forms are found inordinary syphilis. Later we shall consider some biologic peculiarities inthe two groups of spirochetes, but the individual organisms in eachgrou)) are alike in sha))e and in staining reactions.
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Fig. 5.—A localized collection of spirochetes which are not only within thenervous tissues, but are also within the walls of the blood vessel. This is tobe interpreted, according to Hauptmann, as a proliferation of spirochetes intissues in which the blood vessels do not offer enough resistance to preventthe parasites from invading their walls. Figures 5 and 6 are photographic reproductions from Figures 6 and 7 inProfessor Hauptmanns article, Spirochatcn und Hirnrindengefasse beiParalyse, Ztschr. f. d. ges. Xeurol. u. Psychiat.. Orig. 57:122, 1920. PECULIARITIES IN GROLlING AND DISTRIBUTION OF SPIROCHETESIN GENERAL PARALYSIS Three main types of distribution have been described: 1. A diffuse type, in which the organisms are diftusely scattered, without order, usually in small numbers, rarely in large numbers. throughout the grav matter of the nervous tissues. DUXLAP—GEXERAL PARALYSIS 595 2. A focal type in which they are grouped together, sometimes inswarms Hke swarms of bees, often

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