File:Histopathology of collapsing glomerulopathy.jpg
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DescriptionHistopathology of collapsing glomerulopathy.jpg |
English: Histopathology of collapsing glomerulopathy. (A,B) Periodic Acid Schiff (PAS) and Jones Methenamine Silver (JMS) (40×), respectively show intense podocyte hyperplasia and glomerular tuft collapse. (C) JMS (20×) exhibits microcytic transformation of distal convoluted tubules with accumulations of hyaline material inside of those. (D,E) Fluorescence microscopy (40×) shows, respectively, IgM and C3 trapping in areas of collapse/sclerosis. (F) Semi-fine stained in Toluidine Blue (63×) with collapse of the entire glomerular tuft and hyperplasia of podocytes and dilated Bowman’s space. (G,H) Transmission electron microscopy contrasted with Osmium Tetroxide, Lead Citrate and Uranyl in block shows capillary loop collapse with hyalinosis in addition to diffuse fusion and flattening of the pedicels associated with microvillous transformation. (I) Electron microscopy tubes contrasted with osmium tetroxide, lead citrate, and uranyl in block with detail of disorganization of the cytoskeleton in the podocyte cytoplasm, with extensive effacement of the pedicels. |
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Cutrim ÉMM, Neves PDMM, Campos MAG, Wanderley DC, Teixeira-Júnior AAL, Muniz MPR (2022). "Collapsing Glomerulopathy: A Review by the Collapsing Brazilian Consortium.". Front Med (Lausanne) 9: 846173. DOI:10.3389/fmed.2022.846173. PMID 35308512. PMC: 8927620. - CC-BY 4.0 license |
Author | Cutrim ÉMM, Neves PDMM, Campos MAG, Wanderley DC, Teixeira-Júnior AAL, Muniz MPR |
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current | 16:11, 17 October 2023 | 4,550 × 3,449 (2.52 MB) | Mikael Häggström (talk | contribs) | Uploaded a work by Cutrim ÉMM, Neves PDMM, Campos MAG, Wanderley DC, Teixeira-Júnior AAL, Muniz MPR from {{cite journal| author=Cutrim ÉMM, Neves PDMM, Campos MAG, Wanderley DC, Teixeira-Júnior AAL, Muniz MPR | display-authors=etal| title=Collapsing Glomerulopathy: A Review by the Collapsing Brazilian Consortium. | journal=Front Med (Lausanne) | year= 2022 | volume= 9 | issue= | pages= 846173 | pmid=35308512 | doi=10.3389/fmed.2022.846173 | pmc=8927620 | url=https://www.ncbi.nlm.nih.gov/entr... |
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