File:Histopathology of tubulovillous adenoma.jpg

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English: Low magnification micrograph of a tubulovillous adenoma, TVA. Surgical specimen. H&E stain.

TVAs are precancerous lesions that have a mixture a villous morphology and tubular morphology, where the villous component is <50% of the lesion, but greater or equal to 25% of the lesion.

TVAs have nuclear changes like those in tubular adenomas and villous adenomas:

  • Nuclear elongation; elliptical nuclei,
  • Nuclear crowding/pseudostratification.

Morphologic changes include:

  • Loss of goblet cells,
  • Hyperchromatic ("open") nuclei at the luminal surface.

Tubular morphology:

  • Round gland-like structures.

Villous morphology:

  • Long finger-like projections; similar in appearance to villi.
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Mikael Häggström, M.D. Author info
- Reusing images
- Conflicts of interest:
  None

Mikael Häggström, M.D.

[[Category:Mikael Häggström/{{{cat}}}]]
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Camera location41° 24′ 17.72″ N, 73° 26′ 47.49″ W  Heading=240.67146° Kartographer map based on OpenStreetMap.View this and other nearby images on: OpenStreetMapinfo

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current23:29, 13 August 2020Thumbnail for version as of 23:29, 13 August 20202,053 × 1,233 (890 KB)Mikael Häggström (talk | contribs)Uploaded own work with UploadWizard

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