File:SpaceX CRS-21 Scientific Payload Preparations - Brain Organoids, Bacterial Adhesion and Corrosion, Micro-14.webm

English: SpaceX CRS-21 Scientific Payload Preparations: Brain Organoids, Bacterial Adhesion and Corrosion, Micro-14 0:00 - 1:26: Space Tango engineers testing the organoid agitation system and the microscope backlighting for brightfield imaging. All systems are entirely automated. The Effect of Microgravity on Human Brain Organoids (Space Tango-Human Brain Organoids) observes the response of brain organoids to microgravity. Small living masses of cells that interact, grow, and can survive for months, organoids provide a model system for understanding responses and adaptations to changes in the environment. This investigation demonstrates how exposure to microgravity affects survival, metabolism, and features of brain cells and, therefore, cognitive function. 1:27 - 2:17: Space Tango program scientist feeding the organoids in preparation for loading. 2:18 - 2:30: Powered Ascent Utility Locker (PAUL) 2:31 - 4:37: Polymicrobial Biofilm Growth and Control during Spaceflight (Bacterial Adhesion and Corrosion) explores the formation under microgravity conditions of multi-species biofilms, which may behave differently from single-species biofilms. 4:38 - 6:22: The Characterizing the Effects of Spaceflight on the Candida albicans Adaptation Response (Micro-14) investigation aboard the International Space Station (ISS) extends previous flight and ground-based studies on an opportunistic yeast, Candida albicans, to define mechanisms that lead to cellular adaptation responses to the spaceflight environment.